Piperacillin Tazobactam

Product Description

Product Name: Pious 4.5
Composition:
Each vial contains:

• Piperacillin Sodium equivalent to Piperacillin 4 g

• Tazobactam Sodium equivalent to Tazobactam 0.5 g
  Dosage Form: Powder for Injection (IV Use)

---

Description:

Pious 4.5 is a powerful broad-spectrum antibiotic injection combining Piperacillin, an extended-spectrum penicillin, with Tazobactam, a -lactamase inhibitor. This combination is effective against a wide range of Gram-positive and Gram-negative bacteria, including many -lactamase producing organisms.

---

Indications:

Pious 4.5 is indicated in the treatment of moderate to severe infections such as:

• Lower respiratory tract infections (e.g., pneumonia)

• Intra-abdominal infections

• Urinary tract infections

• Skin and soft tissue infections

• Gynecological infections

• Septicemia

• Bone and joint infections

• Febrile neutropenia (as empirical therapy)

• Hospital-acquired infections

---

Mechanism of Action:

• Piperacillin disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs).

• Tazobactam inhibits -lactamase enzymes that would otherwise degrade Piperacillin, enhancing and extending its antibacterial spectrum.

---

Dosage & Administration:

• Adults and children >12 years: 4.5 g IV every 68 hours depending on infection severity

• Administer by intravenous infusion over 30 minutes

• Dose adjustments may be required in renal impairment

Note: Use only under the guidance of a registered medical practitioner. Follow reconstitution and dilution instructions as per standard protocol.

---

Key Features:

• Broad-spectrum coverage against aerobic and anaerobic pathogens

• Effective in polymicrobial and hospital-acquired infections

• Combats -lactamase producing strains

• Trusted choice in critical care and ICU settings

---

Packaging:

• Glass vial containing sterile powder

• May be supplied with a sterile water ampoule (if needed)

---

Broad-Spectrum Anti-Bacterial Action

Piperacillin Tazobactam combines the extended-range antibiotic Piperacillin with Tazobactam, a beta-lactamase inhibitor. This powerful pairing is effective against a wide variety of bacteria, providing reliable therapy for severe infections. Its use is ideally suited for hospital settings where resistant bacterial strains are prevalent.


Convenient Injectable Formulation

Supplied as a dry powder in a sterile vial, Piperacillin Tazobactam is intended for reconstitution and intravenous administration. This formulation type ensures rapid delivery of the active ingredients, making it an essential option for acute care and emergency scenarios where quick patient response is crucial.


Safe Storage and Handling

For maximum stability and to maintain potency, Piperacillin Tazobactam should be stored in a cool, dry, and dark location. Careful storage according to guidelines minimizes degradation of the active ingredients and helps ensure patient safety during use.